刺針月刊: 輝瑞復必泰"疫苗"的功効是0.46%
Lancet: the efficacy of the Pfizer "vaccine" is 0.46%
by DRAFTING
The narrative told you half the truth, namely that the vaccine (experimental drug) from Pfizer-BionTech has a 95% reduction in the risk of taking Covid, that of Moderna by 94%, Astra Zeneca and Johnson & Johnson by 67%.
敘述告訴了你真相的一半，即來自輝瑞-復必泰的疫苗（實驗藥物）降低得到冠狀病毒風險的95％，而莫得納降低94％，阿斯利康和强生降低67％。
But this is the RRR (Relative Risk Reduction) index. On the other hand, what matters is the ARR (Absolute Risk Reduction) Index , which is what really affects it, which varies between populations and time.
但這是RRR（相對風險降低）指數; 另一方面，關事的是ARR（絕對風險降低）指數，這才是真正有影響的指數，它隨著人群和時間的不同而轉變。
Unfortunately, comparing vaccines based on currently available (interim) study data is made even more difficult by disparate study protocols, including primary endpoints (such as what is considered a COVID-19 case and when it is evaluated), types of placebo, study populations, background risks of COVID-19 during the study, duration of exposure, and different definitions of populations for analysis both within and between studies, as well as endpoint definitions and statistical methods for effectiveness.
Importantly, we are left with the unanswered question of whether a vaccine with a given efficacy in the study population will have the same efficacy in another population with different levels of background risk of COVID-19. This is not a trivial question because the intensity of transmission varies from country to country, influenced by factors such as public health interventions and virus variants. The only indication reported on the effectiveness of the vaccine is the Israeli mass vaccination campaign using the Pfizer - BioNTech product. Although the design and methodology are radically different from the randomized study,Dagan and colleagues, report a 94% RRR, which is essentially the same as the Phase 3 study RRR (95%) but with an ARR of 0.46%, which translates into an NNV (Number Needed to Vaccinate) of 217 (when the ARR was 0.84%) and the NNV was 119 in the phase 3 study). This means that in a real-life setting, 1.8 times more subjects may need to be vaccinated to prevent one more case of COVID-19 than expected in the corresponding clinical trial.
And all this without taking into account that there remains the possibility of infecting, being infected and having adverse side effects. In the face of vaccination effectiveness. Now, you can understand why they fielded an army general.
而所有這些都並沒有考慮到仍然存在感染、被感染以及具有不良副作用的可能性，不顧疫苗接種的有效性。
現在你能明白他們為何派遣一名將軍上場。
https://www.miglioverde.eu/lancet-lefficacia-del-vaccino-pfizer-e-dello-046/
沒有留言:
發佈留言