維他命B6 和蛋氨酸削減肺癌風險50%

維他命 B6 和蛋氨酸削減肺癌風險50%
Vitamin B6 and methionine slash lung cancer risk by 50 percent
Tuesday, June 29, 2010
by: S. L. Baker, features writer

(NaturalNews) Lung cancer, which usually develops in the cells lining air passages, will be diagnosed in about 222,520 Americans this year, according to the National Cancer Institute (NCI). In addition, the NCI says nearly half that many people -- about 157,300 -- will die from the disease in 2010.

Although lung cancer is notoriously difficult to treat successfully, French scientists have discovered several natural substances that offer substantial protection from the malignancy. In a huge study of almost 400,000 participants, those who had higher blood levels of vitamin B6 and the essential amino acid methionine (found in many forms of protein) had the lowest risk of lung cancer -- even those who were former or current smokers.

For the study, which was just published in the Journal of the American Medical Association (JAMA), Paul Brennan, Ph.D., of the International Agency for Research on Cancer, Lyon, France, and colleagues documented B vitamins and methionine levels based on serum samples from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. In all, they investigated 385,747 research subjects from 10 European countries. By 2006, 899 had been diagnosed with lung cancer; they were compared to 1,770 control participants and all were individually matched by country, sex, date of birth, and date of blood collection.

The results of the researchers' analysis revealed a dramatically lower risk for lung cancer among participants with the highest blood levels of B6 and methionine. In addition, a moderately lower risk for lung cancer in former and current smokers was observed in those with higher serum levels of folate.

"Similar and consistent decreases in risk were observed in never, former, and current smokers, indicating that results were not due to confounding (factors that can influence outcomes) by smoking. The magnitude of risk was also constant with increasing length of follow-up, indicating that the associations were not explained by preclinical disease," the researchers stated in their JAMA article.

肺癌減少50%
50 percent reduction in lung cancer
"Our results suggest that above-median serum measures of both B6 and methionine, assessed on average five years prior to disease onset, are associated with a reduction of at least 50 percent on the risk of developing lung cancer. An additional association for serum levels of folate was present, that when combined with B6 and methionine, was associated with a two-thirds lower risk of lung cancer," the scientists wrote.

So how could these natural substances keep lung cancer at bay? The key may be found in previous research which has shown that B vitamin deficiencies likely increase the probability of DNA damage and subsequent gene mutations. "Given their involvement in maintaining DNA integrity and gene expression, these nutrients have a potentially important role in inhibiting cancer development, and offer the possibility of modifying cancer risk through dietary changes," the authors concluded. They also pointed out that B vitamin deficiencies are known to be high in many western populations.

Additional good news about lung protection was presented earlier this year at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference. Scientists have found eating a handful of pistachios daily may offer significant protection from lung cancer (http://www.naturalnews.com/027732_p...).

http://www.naturalnews.com/029097_lung_cancer_vitamin_B6.html

血液維他命B6多寡　關係肺癌風險
(法新社)2010年6月16日 星期三 09:35
（法新社華盛頓 15日電） 癌症專家今天表示，血液中維他命B6和必需胺基酸含量較高的抽菸人士，發展出肺癌的風險，較缺少這些營養素的抽菸者要低。

一份在歐洲10國針對近40萬名抽菸者和已戒菸者所進行的研究顯示，血液中維他命B6和必需胺基酸的蛋氨酸（methionine）含量較高的人，罹患肺癌的機率至少掉了一半。

然而研究人員未在結論中認定，服用較多的維他命B6和必需胺基酸，能減少肺癌風險，並強調戒菸的重要性。

除了血液的維他命B6和蛋氨酸成分，已戒菸者或抽菸者若有較高的血清葉酸，罹患肺癌的風險更少了67%。

根據世界衛生組織 （WHO）統計，全球每年有130萬人死於肺癌，佔所有癌症死亡人數的18%。

這項研究刊登在「美國 醫學會期刊」（Journal of the American Medical Association），文中還提及許多戒菸者和為數不少的不抽菸者（特別是部分亞洲國家婦女）都罹患肺癌。（譯者：中央社賴秀如）

http://hk.news.yahoo.com/article/100616/8/inmk.html