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2012年2月7日星期二

超級細菌性肺炎:37州、50%死亡率

超級細菌性肺炎:37州、50%死亡率
Superbug Pneumonia: 37 States, 50% Mortality Rate
Heather Callaghan
Activist Post
Monday, February 6, 2012
Translation by Autumnson Blog

This is possibly our biggest infection control dilemma yet.
然而這可能是我們最大的感染控制困境。
Although cases of this particular pneumonia infection have been on the rise worldwide for the past 10 years, there is an alarming spread recently across the US.
雖然這種特別的肺炎感染個案在過去的十年已一直世界性上升,但最近在美國以一驚人的速度擴散。
What makes this opportunistic “superbug” such a nightmare is that it is Carbapenem-Resistant, meaning “last resort antibiotic” resistant. It’s a Carbapenem-Resistant Klebsiella pneumoniae (CRKP); Klebsiella pneumoniae is a strain of Klebsiella which is related to E. Coli and Salmonella from the family Enterobacteriaceae.
是什麼使這投機取巧的“超級病菌”成為這樣的一場噩夢,是因為它是碳青黴烯類耐藥,意即是“最後手段抗生素”耐藥。它是碳青黴烯類耐藥克雷伯菌肺炎(CRKP);克雷伯菌肺炎是克雷伯菌的菌株,是與大腸桿菌和來自家庭腸桿菌的沙門氏菌有關。
Thirty-seven states plus Washington D.C. and Puerto Rico have reported the outbreak, up from thirty-five states last year. The CDC believes it is also spreading in 14 other US territories but is going unreported.
37個州加上華盛頓首都和波多黎各都已報告疫情爆發,從去年的三十五州上升。疾病預防控制中心相信,它亦散佈在其它14個美國領土,但將不會報告。
Found inside the gut; outside of the gut, it can cause lethal infection. The major reservoirs of infection are the gastrointestinal tracts of patients, catheters, ventilators, unclean instruments, and the hands of hospital personnel. It zeros in on hospitals, ICUs, long-term care facilities like nursing homes, and those with immune-compromised conditions.
發現在腸道內;在腸道之外,它能導致致命感染。感染的主要水庫是患者的胃腸道、導管、呼吸器、不潔的工具和醫院工作人員的手。它歸零在醫院、加護病房、長期護理設施如養老院、和那些有免疫能力較差條件的人。
It is a potential community-acquired type of pneumonia (one not acquired from hospitals) and the bug has an incredible ability to mutate and resist. It does indeed carry a fatality rate of up to 50 percent or more! That's 10 percent more than last year's reports.
它是一種潛在的社區獲得肺炎類型(不從醫院獲得)和病菌有一種令人難以置信的變異和抵禦能力。它確實帶有病死率高達50%或以上!是比去年的報告多10%。
There are a couple of antibiotics that have been shown to kill these superbugs, but can also risk death for CRKP victims. Even the FDA cautions that some of the last resort antibiotics create an "increased risk of death" in pneumonia patients.

According to medical officer Alexander Kallen of the CDC last year, “failure to recognize CRE infections when they first occur in a facility has resulted in a missed opportunity to intervene before these organisms are transmitted more widely."

Now is an ideal time to avoid typical healthcare facilities and make or stock colloidal silver -- the best defense against resistant superbugs such as CRKP.
http://www.activistpost.com/2012/02/superbug-pneumonia-37-states-50.html

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