2011年01月10日08:19
來源：國際在線
據英國《每日郵報》1月6日報道，美國研究人員開發出一種新型戒毒疫苗，可以幫助吸毒者擺脫毒癮。
領導這項研究的羅納德·克裡斯托爾教授說：“大量數據顯示，我們能夠保護老鼠免受可卡因的影響，這種方法在幫助人類對抗毒癮時也將非常有效。”他說，這種疫苗能夠在可卡因分子到達老鼠大腦前將其“綁定”，預防出現與可卡因有關的極度興奮症狀。
這種疫苗可以釋放一種結構與可卡因分子相似的化學物質，然后附在感冒病毒上。注入人體后，人體免疫機制就會發揮作用，將這種化學物質視為“入侵者”。一旦這種“新入侵者”的結構被確認，自然免疫機制就會形成可卡因抗體。當再遇到可卡因分子時，這種抗體就會迅速產生，吞噬可卡因分子，令其難以到達大腦。
克裡斯托爾在《分子醫學》網站上寫道，這種疫苗的效果可以持續至少13周。在所有嘗試開發可卡因疫苗的試驗中，這種疫苗是第一種不需要多次注射、而且能夠快速進入人體試驗的疫苗。克裡斯托爾認為，通過按照比例增加劑量，這種疫苗也應該適用於人類。(楊柳)
http://scitech.people.com.cn/BIG5/13687680.html
新酗酒疫苗製成
New alcoholism vaccine is made
Sat Jan 8, 2011 3:52PM
Translation by Autumnson Blog
Chilean scientists have developed a new vaccine against alcoholism that gives the sensation of a terrible hangover after just a few drinks.
智利科學家已開發出一種新疫苗對付酗酒，衹短短的幾杯便給予一可怕的宿醉感覺。
The new alcoholism vaccine, which works like patches used for kicking smoking, is believed to be more efficient as it specifically targets liver cells.
新的酗酒疫苗，如戒煙貼般運作，被認為是更有效因為它專門針對肝細胞。
It works by neutralizing aldehyde dehydrogenase, a group of enzymes that metabolizes alcohol and are therefore responsible for alcohol tolerance, said the lead Chilean researcher Juan Asenjo.
它通過中和醛脫氫酶 - 一組的酶使酒精新陳代謝，和因此對酒精的耐藥量負責，領先智利研究員胡安阿森霍說。
Apart from contributing to a general feeling of ''unease,'' the vaccine would increase nausea, heartbeat and sweating following drinking alcohol.
除了造成一般的"不安"感覺，在飲酒下疫苗將增加噁心、心跳及冒汗。
"The therapy has been tested in rats that are genetically alcoholics, and has worked successfully to decrease the addiction by 50 percent," researchers said, hoping that the vaccine may reduce the alcohol consumption by 90-95 percent.
Researchers said further animal tests would be conducted this year before the human trials are launched in 2012.
"In one to two years we will start testing patients. If the result in humans is similar to the results we saw in animals, one shot a month would be sufficient at the beginning to … help alleviate the addiction," Asenjo said.
SJM/PKH
http://www.presstv.ir/detail/159226.html
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