蓋茨基金會在研究汗誘發疫苗

比爾和梅林達蓋茨基金會在研究汗誘發疫苗
The Bill & Melinda Gates Foundation working on Sweat-Triggered Vaccines
The Bill & Melinda Gates Foundation
10.05.2010

Foundation Funds 78 New Innovative Global Health Projects, Including Cell Phone Blood Tests, Carnivorous Plants, and Sweat-Triggered Vaccines
基金會金援78項新的全球性創新的衛生計劃，包括手機驗血、食蟲植物、與汗誘發疫苗
Grants from 18 countries poised to help prevent and diagnose infectious disease and promote family health
同意來自 18個國家以準備幫助預防，和診斷傳染性疾病，及促進家庭健康
LONDON — The Bill & Melinda Gates Foundation today announced 78 grants of US$100,000 each in the latest round of Grand Challenges Explorations. Grants include the development of a low-cost cell phone microscope to diagnose malaria, study of the strategic placement of insect-eating plants to reduce insect-borne diseases, and investigation of nanoparticles to release vaccines when they come in contact with human sweat. The grants support research across 18 countries and six continents.
倫敦 - 比爾和梅林達蓋茨基金會今天宣布，78項每項10萬美元的 補助金在最新一輪的大挑戰探索。補助金包括開發低成本手機顯微鏡去診斷瘧疾，食蟲植物的戰術性定位研究以減少昆蟲傳播的疾病，及納米粒子研究以釋放疫苗當疫苗接觸人的汗水。補助金支持研究橫跨 18個國家和6個大洲。
“Grand Challenges Explorations continues to generate unique and creative ways to tackle global health issues,” said Dr. Tachi Yamada, president of the Gates Foundation’s Global Health Program. “We are convinced that some of these ideas will lead to new innovations and eventually solutions that will save lives.”

This year’s European grantees are based at universities, research institutes and non-profit organizations. The winners represent groups in Germany, Sweden, Norway and the UK.

Some examples of the breadth of projects funded this round include:
這一輪資助項目的一些例子的廣度包括：
More effective vaccines:
更有效的疫苗：
Sweat-triggered vaccine delivery: Carlos Alberto Guzman of the Helmholtz Centre for Infection Research in Germany with Claus-Michael Lehr and Steffi Hansen of the Helmholtz-Institute for Pharmaceutical Research will develop nanoparticles that penetrate the skin through hair follicles and burst upon contact with human sweat to release vaccines.
汗誘發的疫苗交付：......將開發納米粒子，它們會透過毛囊滲透皮膚，和爆發當接觸人的汗水去釋放疫苗。
A “seek-and-destroy” laser vaccine: Owain Millington and Gail McConnell of University of Strathclyde in the United Kingdom will use existing imaging systems to identify and destroy Leishmania parasites with a targeted laser;
一種“搜索和摧毀”的激光疫苗：......將使用現存的成像系統，去識別和摧毀利甚曼寄生蟲以針對性的激光;

New strategies to fight malaria:

Insecticide-treated traditional scarves: David Sintasath of the Malaria Consortium in Thailand will research whether treating traditional scarves worn by migrant workers along the Thai-Cambodia border with insecticides will reduce the rate of drug-resistant malaria.

Cell phone microscope to diagnose malaria: Aydogan Ozcan of the University of California, Los Angeles in the U.S. will test a low-cost, compact cell phone microscope to diagnose malaria in field settings.


Solutions to promote family health:

Ultrasound as a reversible male contraceptive: James Tsuruta and Paul Dayton of the University of North Carolina, Chapel Hill in the U.S. will study the ability of ultrasound to temporarily deplete testicular sperm counts for possible use as new contraceptive method for men.

Grand Challenges Explorations is a five-year, $100 million initiative to promote innovation in global health. It is part of the Grand Challenges in Global Health initiative which is supported by the Gates Foundation to achieve major breakthroughs in global health.

Applications for the next round of Grand Challenges Explorations are being accepted through May 19, 2010.

Grant application instructions, including the list of topic areas in which proposals are currently being accepted, are available at the Grand Challenges Explorations website: http://www.grandchallenges.org/.

http://www.wiseupjournal.com/?p=1541

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